The majority of bleeding episodes in hemophilic patients occur within the joints. Of these hemarthroses, the knees, elbows, and ankles account for almost 80%. Should the bleeding persist, the synovium starts to hypertrophy and a vicious cycle of chronic synovitis develops, leading to joint destruction.
In immature articulation, synovitis causes hypertrophy of the epiphyseal growth plates and significant structural deficiencies may rapidly develop. This stimulus to the growth plates results in bone hypertrophy, leg length discrepancy, and angular deformities.
In mature articulation, hemophilia has a major detrimental effect on the joint cartilage. As it progressively exacerbates, joint function deteriorates. Loss of joint space is the most important radiographic finding related to range of motion. As the synovium becomes increasingly scarred, there is gradual conversion from friable hyperemic tissue to fibrotic scar tissue. This process is the natural course of hemophilic arthropathy.
Originally posted by: Rodríguez-Merchán, E. C. MD, PhDSection Editor(s): Heim, Michael MBChB; Horoszowski, Henri MD
Information has just been posted on the National Hemophilia Foundation’s website on Washington Days, NHF’s premiere lobbying event. NHF will be in Washington D.C. from
Wednesday February 23, through Friday 25, 2011.
Dates have changed to Wednesday, February 16 through Friay, February 18, 2011.
Affinity Biotech is passionate about customer independence. We encourage all of our patients to become independent and self sufficient, especially when it comes to dealing with their Hemophilia.
This article from HemAware gives great advice to parents on how to help their child become more independent and why it is important.
Read more at HemAware.com
Joe Moleski was born with hemophilia. At six months old, bleeding on his brain almost killed him. Before his first birthday, he had two full-body blood transfusions. Now, the vibrant 22-year-old University of Missouri–St. Louis biology senior is applying to medical schools – 30 to be exact – so that he can help children with his same condition…
Continue reading in the University of Missouri Newsroom
Health Care Reform is happening and we all have questions. Here is a great article we found that defines what the new law will mean for you. Here, have a look…
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